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1, Bacitracin is discovered by B.H.johnson in 1973 from Bacillus Sub tilis in the wounds of patients. It now has been produced industrially. Bacitracin consists of A, B1, B2, B3, and A owns the best effects and highest concentration, the ferment product contains about 40% of A. A can react with Zn2+ and produce Zinc Bacitracin. With the similar anti-bacterial spectrum to penicilling, Zinc Bacitracin can offer strong antibacterial effects to Gram-positive bacteria. Now, it is mainly used in the therapy of systemic infection and local infection causedby Gram-positive bacteria; especially for patient who resists penicillin.
2, Produced by B.polymyxa, polymyxin B sulphate is a general name of basic polypeptide type antibiotics. In known antibiotics, polymyxin offers the highest antibacterial effects to Gram-negative bacteria, especially for the therapy of meningitis and dysentery with bloody stool infected by Gram-negative bacteria. Specially, it can kill pseudomonas aeruginosa and became drug-fast, thus it can be used in the therapy of scalding,infection after surgical operation, dysentery with bloody stool and other diseases caused by Gram-negative bacteria.
3, Zinc Bacitracin can work with polymyxin B sulphate and offer broad antibacterial spectrum. Because both of Zinc Bacitracin and polymyxin B sulphate are polypeptide antibiotics, thus their co-work can be used in bigger application ranges. Now, these two products are well sold in EU, USA, Southeast Asia and West Asia, and In line with the current EP, USP regulations. We rank the leading position in these fields in the world. |
